BDBM50149339 4-Methyl-8-phenylethynyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quinolin-3-one::CHEMBL117159

SMILES CC1=C2CCc3cc(ccc3N2CCC1=O)C#Cc1ccccc1

InChI Key InChIKey=UCJOFTDYXWOYHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149339   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50149339(4-Methyl-8-phenylethynyl-1,2,5,6-tetrahydro-pyrido...)
Affinity DataIC50: 8.75nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50149339(4-Methyl-8-phenylethynyl-1,2,5,6-tetrahydro-pyrido...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human steroid 5-alpha-reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed