BDBM50149515 CHEMBL181593::[6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-pyrimidin-4-yl]-(2,4,6-trimethyl-phenyl)-methanone

SMILES CCCN(CC1CC1)c1nc(C)nc(C(=O)c2c(C)cc(C)cc2C)c1C

InChI Key InChIKey=CGGIHGFGMZBHBI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149515   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149515([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataKi:  15nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149515([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed