BDBM50149828 2-Amino-6-(2-cyclobutylmethoxy-6-hydroxy-phenyl)-1'',2'',3'',4'',5'',6''-hexahydro-[4,4'']bipyridinyl-3-carbonitrile::CHEMBL361841

SMILES Nc1nc(cc(C2CCNCC2)c1C#N)-c1c(O)cccc1OCC1CCC1

InChI Key InChIKey=YCBMOJCSUJUUBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149828   

LigandPNGBDBM50149828(2-Amino-6-(2-cyclobutylmethoxy-6-hydroxy-phenyl)-1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50149828(2-Amino-6-(2-cyclobutylmethoxy-6-hydroxy-phenyl)-1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed