BDBM50149871 (R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)propyl)(methyl)amino)acetic acid::CHEMBL180966::{[(R)-3-(biphenyl-4-yloxy)-3-(4-fluoro-phenyl)-propyl]-methyl-amino}-acetic acid
SMILES CN(CC[C@@H](Oc1ccc(cc1)-c1ccccc1)c1ccc(F)cc1)CC(O)=O
InChI Key InChIKey=FDORQEIHOKEJNX-HSZRJFAPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50149871
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]glycine uptake at rat glycine transporter 1 expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human GlyT-1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human GlyT1 expressed in QT6 cells assessed as reduction in [14C]glycine uptake incubated for 20 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillati...More data for this Ligand-Target Pair