BDBM50150191 2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-nitro-phenoxy)-pyran-4-one::CHEMBL129473

SMILES Cc1cc(=O)c(Oc2ccc(cc2)[N+]([O-])=O)c(o1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=ZFAKGXCOCAOOIN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150191   

TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150191(2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-nitro-p...)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition concentration against cyclooxygenase-2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150191(2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-nitro-p...)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibitory concentration for Cyclooxygenase-2 (Prostaglandin G/H synthase 2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150191(2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-nitro-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition concentration against cyclooxygenase-1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed