BDBM50150193 3-(2-Chloro-4-methoxy-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one::CHEMBL126369

SMILES COc1ccc(Oc2c(oc(C)cc2=O)-c2ccc(cc2)S(C)(=O)=O)c(Cl)c1

InChI Key InChIKey=KQVXEUPXZOZBRD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150193   

TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150193(3-(2-Chloro-4-methoxy-phenoxy)-2-(4-methanesulfony...)
Affinity DataIC50: 180nMAssay Description:Inhibition concentration against cyclooxygenase-2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150193(3-(2-Chloro-4-methoxy-phenoxy)-2-(4-methanesulfony...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration for Cyclooxygenase-2 (Prostaglandin G/H synthase 2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150193(3-(2-Chloro-4-methoxy-phenoxy)-2-(4-methanesulfony...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition concentration against cyclooxygenase-1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150193(3-(2-Chloro-4-methoxy-phenoxy)-2-(4-methanesulfony...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibitory concentration for Cyclooxygenase-1 (Prostaglandin G/H synthase 1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed