BDBM50150202 2-(4-Methanesulfonyl-phenyl)-6-methyl-3-o-tolyloxy-pyran-4-one::CHEMBL126303

SMILES Cc1cc(=O)c(Oc2ccccc2C)c(o1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=QFGVWVQHHYWJKM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150202   

TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150202(2-(4-Methanesulfonyl-phenyl)-6-methyl-3-o-tolyloxy...)
Affinity DataIC50: 170nMAssay Description:Inhibition concentration against cyclooxygenase-2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150202(2-(4-Methanesulfonyl-phenyl)-6-methyl-3-o-tolyloxy...)
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration for Cyclooxygenase-2 (Prostaglandin G/H synthase 2) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Devi Ahilya Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50150202(2-(4-Methanesulfonyl-phenyl)-6-methyl-3-o-tolyloxy...)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibitory concentration for Cyclooxygenase-1 (Prostaglandin G/H synthase 1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Devi Ahilya Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50150202(2-(4-Methanesulfonyl-phenyl)-6-methyl-3-o-tolyloxy...)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition concentration against cyclooxygenase-1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed