BDBM50150337 (R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl]-methyl-amino}-hexanoic acid::CHEMBL182883

SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C[C@@H](O)C[C@@H](O)CC(O)=O

InChI Key InChIKey=VSBFTVFWFJKINP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150337   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50: 18nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150337((R)-5-(S)-Hydroxy-3-hydroxy-6-{[4-((8S,11R,13S,14S...)
Affinity DataIC50: 130nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed