BDBM50150347 3-[4-(4-{[(2,4-Difluoro-benzyl)-(3-methanesulfonylamino-2-methyl-phenyl)-amino]-methyl}-phenoxy)-phenyl]-propionic acid::CHEMBL181729

SMILES Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(Oc2ccc(CCC(O)=O)cc2)cc1)Cc1ccc(F)cc1F

InChI Key InChIKey=RPMFAHWVBZTSBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150347   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150347(3-[4-(4-{[(2,4-Difluoro-benzyl)-(3-methanesulfonyl...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150347(3-[4-(4-{[(2,4-Difluoro-benzyl)-(3-methanesulfonyl...)
Affinity DataIC50: 220nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed