BDBM50150527 2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic acid cyanomethyl-amide::CHEMBL365007

SMILES CC(C)C[C@H](Nc1cscc1Br)C(=O)NCC#N

InChI Key InChIKey=KGJLXDHUTKATFA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150527   

TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50150527(2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50150527(2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 158nMAssay Description:Inhibitory concentration against human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50150527(2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 458nMAssay Description:Inhibitory concentration against human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50150527(2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 897nMAssay Description:Inhibitory concentration against human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed