BDBM50150768 2-Methyl-5-(6-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-phenol::CHEMBL184750

SMILES Cc1cc2c(Nc3ccc(C)c(O)c3)ncnn2c1

InChI Key InChIKey=BNJHLXRPLVJJDL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150768   

TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150768(2-Methyl-5-(6-methyl-pyrrolo[2,1-f][1,2,4]triazin-...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Universita Degli Studi Di Palermo

Curated by ChEMBL
LigandPNGBDBM50150768(2-Methyl-5-(6-methyl-pyrrolo[2,1-f][1,2,4]triazin-...)
Affinity DataIC50: 405nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Universita Degli Studi Di Palermo

Curated by ChEMBL
LigandPNGBDBM50150768(2-Methyl-5-(6-methyl-pyrrolo[2,1-f][1,2,4]triazin-...)
Affinity DataIC50: 650nMAssay Description:In vitro inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150768(2-Methyl-5-(6-methyl-pyrrolo[2,1-f][1,2,4]triazin-...)
Affinity DataIC50: 654nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed