BDBM50150879 CHEMBL185440::N-(4-{(S)-4-Amino-1-[4-(4-methyl-piperazin-1-yl)-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-2-methoxy-phenyl)-benzamide::isoindolinone analog 1b

SMILES COc1cc(ccc1NC(=O)c1ccccc1)-c1nn(C2CC[C@@H](CC2)N2CCN(C)CC2)c2ncnc(N)c12

InChI Key InChIKey=OKRHYXZXYNXSAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150879   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM50150879(N-(4-{(S)-4-Amino-1-[4-(4-methyl-piperazin-1-yl)-c...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed