BDBM50151074 CHEMBL364368::N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-2-yl)-phenyl]-N-methyl-acetamide

SMILES C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(N(C)C(C)=O)cc3)C[C@@]21C

InChI Key InChIKey=ZDCMJDVSSLHLLQ-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50151074   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of glucocorticoid receptor dependent alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi:  8.90nMAssay Description:Inhibition of human androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi:  34nMAssay Description:Inhibition of human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi:  570nMAssay Description:Inhibition of human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi:  790nMAssay Description:Inhibition of human Thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151074BDBM50151074(N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13...)
Affinity DataKi: >2.25E+3nMAssay Description:Inhibition of human Thyroid hormone receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed