BDBM50151196 5-[4-(2-Chloro-benzyl)-piperazin-1-yl]-2-furan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine::CHEMBL177711

SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN(Cc2ccccc2Cl)CC1

InChI Key InChIKey=ZRPMCZFQKIIDAV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151196   

TargetAdenosine receptor A2a(Rat)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151196(5-[4-(2-Chloro-benzyl)-piperazin-1-yl]-2-furan-2-y...)
Affinity DataKi:  180nMAssay Description:Inhibition of [3H]ZM-241,385 binding to rat brain adenosine A2a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151196(5-[4-(2-Chloro-benzyl)-piperazin-1-yl]-2-furan-2-y...)
Affinity DataKi:  180nMAssay Description:Inhibition of [3H]ZM-241385 binding to adenosine A2a receptor of rat brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151196(5-[4-(2-Chloro-benzyl)-piperazin-1-yl]-2-furan-2-y...)
Affinity DataKi: >500nMAssay Description:Inhibition of [3H]DPCPX binding to rat cerebral cortex adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151196(5-[4-(2-Chloro-benzyl)-piperazin-1-yl]-2-furan-2-y...)
Affinity DataKi: >500nMAssay Description:Inhibition of [3H]DPCPX binding to adenosine A1 receptor of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed