BDBM50151517 5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-6-oxo-4-(3-trifluoromethyl-phenyl)-1,6-dihydro-pyridine-2-carbonitrile::CHEMBL183087

SMILES Cn1cncc1C(OCc1c(cc(C#N)n(C)c1=O)-c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N

InChI Key InChIKey=LPLRFECVNFTFFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151517   

LigandPNGBDBM50151517(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 3.60E+3nMAssay Description:inhibitory concentration needed to to reduce the bovine GGTase-catalyzed incorporation of [3H]-FPP into a biotin-linked K-ras (B) decapeptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed