BDBM50151518 4-[[1-(2-Bromo-pyridin-3-ylmethyl)-4-(3-chloro-phenyl)-6-oxo-1,6-dihydro-pyridin-3-ylmethoxy]-(3-methyl-3H-imidazol-4-yl)-methyl]-benzonitrile::CHEMBL185202

SMILES Cn1cncc1C(OCc1cn(Cc2cccnc2Br)c(=O)cc1-c1cccc(Cl)c1)c1ccc(cc1)C#N

InChI Key InChIKey=BRLZCDTWHIVOEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151518   

LigandPNGBDBM50151518(4-[[1-(2-Bromo-pyridin-3-ylmethyl)-4-(3-chloro-phe...)
Affinity DataIC50: 6.60E+3nMAssay Description:inhibitory concentration needed to to reduce the bovine GGTase-catalyzed incorporation of [3H]-FPP into a biotin-linked K-ras (B) decapeptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed