BDBM50151770 3-(2-Chloro-4-methoxy-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carbonitrile::CHEMBL183279

SMILES COc1ccc(Sc2c([nH]c3cc(ccc23)S(C)(=O)=O)C#N)c(Cl)c1

InChI Key InChIKey=VCZLGEIZUGWHAL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151770   

TargetProstaglandin G/H synthase 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151770(3-(2-Chloro-4-methoxy-phenylsulfanyl)-6-methanesul...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151770(3-(2-Chloro-4-methoxy-phenylsulfanyl)-6-methanesul...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151770(3-(2-Chloro-4-methoxy-phenylsulfanyl)-6-methanesul...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 1 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed