BDBM50151782 3-(2,4-Difluoro-benzyl)-6-methanesulfonyl-2-methyl-1H-indole::CHEMBL183970

SMILES Cc1[nH]c2cc(ccc2c1Cc1ccc(F)cc1F)S(C)(=O)=O

InChI Key InChIKey=HEQWADUEXFRBSK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151782   

TargetProstaglandin G/H synthase 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151782(3-(2,4-Difluoro-benzyl)-6-methanesulfonyl-2-methyl...)
Affinity DataIC50: 260nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151782(3-(2,4-Difluoro-benzyl)-6-methanesulfonyl-2-methyl...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151782(3-(2,4-Difluoro-benzyl)-6-methanesulfonyl-2-methyl...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 1 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed