BDBM50152006 3-{4-[4-(2-Cyano-3-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL433968

SMILES COc1cccc(N2CCN(CCCCc3c[nH]c4ccc(cc34)C#N)CC2)c1C#N

InChI Key InChIKey=QMRDAGPTZAPMJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152006   

TargetD(2) dopamine receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50152006(3-{4-[4-(2-Cyano-3-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50152006(3-{4-[4-(2-Cyano-3-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of [3H]5-HT re-uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50152006(3-{4-[4-(2-Cyano-3-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of 8-OH DPAT binding to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed