BDBM50152189 Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl ester 4-(6-amino-purin-9-yl)-tetrahydro-furan-2-ylmethyl ester::[4-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl [5-(6-amino-9H-purin-9-yl)-2-[(phosphonatooxy)methyl]oxolan-3-yl] phosphate

SMILES Nc1ccn(C2COC(COP([O-])(=O)OC3CC(OC3COP([O-])([O-])=O)n3cnc4c(N)ncnc34)C2O)c(=O)n1

InChI Key InChIKey=LPGFNCONVZCCCG-UHFFFAOYSA-K

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152189   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50152189([4-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hyd...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50152189([4-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hyd...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed