BDBM50152192 Phosphoric acid 4-(6-amino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 5-(6-amino-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl ester

SMILES Nc1ncnc2n(cnc12)C1CC(OP([O-])(=O)OCC2OCC(C2O)n2cnc3c(N)ncnc23)C(COP([O-])([O-])=O)O1

InChI Key InChIKey=PMRUSLCJFLHBKX-UHFFFAOYSA-K

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152192   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50152192(Phosphoric acid 4-(6-amino-purin-9-yl)-3-hydroxy-t...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50152192(Phosphoric acid 4-(6-amino-purin-9-yl)-3-hydroxy-t...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed