BDBM50152361 4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-quinolin-4-yl]-piperazine-1-carbothioic acid (4-cyano-phenyl)-amide::CHEMBL186719

SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(cc3)C#N)c(cnc2cc1OCCCN1CCCCC1)C#N

InChI Key InChIKey=ZJOHAEZPXFNGLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152361   

TargetPlatelet-derived growth factor receptor beta(Human)
In Vivo Sciences Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152361(4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
In Vivo Sciences Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152361(4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed