BDBM50152369 4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-piperazine-1-carbothioic acid (6-trifluoromethyl-pyridin-3-ylmethyl)-amide::CHEMBL184244

SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1ccc(nc1)C(F)(F)F

InChI Key InChIKey=KMPKNQLUSHGOEZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152369   

TargetPlatelet-derived growth factor receptor beta(Human)
In Vivo Sciences Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152369(4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
In Vivo Sciences Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152369(4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Platelet derived growth factor receptor beta autophosphorylation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
In Vivo Sciences Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152369(4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...)
Affinity DataIC50: 1.03E+3nMAssay Description:In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed