BDBM50152548 4-Biphenyl-3-yl-2,4-dioxo-butyric acid::CHEMBL185787::CHEMBL197721

SMILES OC(=O)C(=O)CC(=O)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=RBUSCVCLCFESHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152548   

TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152548(CHEMBL197721 | CHEMBL185787 | 4-Biphenyl-3-yl-2,4-...)
Affinity DataIC50: 3.24E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152548(CHEMBL197721 | CHEMBL185787 | 4-Biphenyl-3-yl-2,4-...)
Affinity DataIC50: 3.62E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50152548(CHEMBL197721 | CHEMBL185787 | 4-Biphenyl-3-yl-2,4-...)
Affinity DataIC50: 2.80E+4nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed