BDBM50152557 2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophen-2-yl]-butyric acid::CHEMBL182756

SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=CBRIPJMCSCGSGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152557   

TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152557(2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophe...)
Affinity DataIC50:  440nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152557(2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophe...)
Affinity DataIC50:  310nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed