BDBM50152562 4-(3,4''-Dichloro-biphenyl-4-yl)-2,4-dioxo-butyric acid::CHEMBL183257

SMILES OC(=O)C(=O)CC(=O)c1ccc(cc1Cl)-c1ccc(Cl)cc1

InChI Key InChIKey=XHURXRSUVMLPLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152562   

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152562(4-(3,4''-Dichloro-biphenyl-4-yl)-2,4-dioxo-butyric...)
Affinity DataIC50: 410nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152562(4-(3,4''-Dichloro-biphenyl-4-yl)-2,4-dioxo-butyric...)
Affinity DataIC50: 1.77E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed