BDBM50152567 2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-butyric acid::CHEMBL367585

SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)C(F)(F)F

InChI Key InChIKey=LCARJFQPJXGRFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152567   

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152567(2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-buty...)
Affinity DataIC50: 1.52E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152567(2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-buty...)
Affinity DataIC50: 2.32E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed