BDBM50152574 2,4-Dioxo-4-thiophen-2-yl-butyric acid::CHEMBL183604

SMILES OC(=O)C(=O)CC(=O)c1cccs1

InChI Key InChIKey=MWRKICQKTVHQBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152574   

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152574(2,4-Dioxo-4-thiophen-2-yl-butyric acid | CHEMBL183...)
Affinity DataIC50: 1.01E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152574(2,4-Dioxo-4-thiophen-2-yl-butyric acid | CHEMBL183...)
Affinity DataIC50: 3.87E+4nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed