BDBM50152799 (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-(piperidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide::(R)-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(2-(1-(piperidin-3-ylamino)ethyl)phenyl)piperazin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-(piperidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide::CHEMBL360716
SMILES CC(NC1CCCNC1)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1
InChI Key InChIKey=NKVAOVHVGQNSIX-CVZNUHMCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50152799
Affinity DataKi: 6.40nMAssay Description:Displacement of [125]NDP-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Displacement of [125I]NDP-MSH from HEK293 cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Binding affinity towards human melanocortin 4 receptor expressed in HEK 293 cells using [125I]NDP-MSHMore data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Displacement of [125I]NDP-MSH from HEK293 cells expressing human melanocortin-5 receptorMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Displacement of [125I]-NDP-MSH from HEK293 cells expressing human melanocortin-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of [125I]NDP-MSH from HEK293 cells expressing human melanocortin-3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.70nMAssay Description:Effective concentration for cAMP release in HEK293 cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.70nMAssay Description:Agonistic effective concentration to stimulate cAMP in CHO cells stably expressing the human melanocortin-4 receptor More data for this Ligand-Target Pair
Affinity DataEC50: 3.80nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 3.80nMAssay Description:Effective concentration against cAMP release in CHO cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair