BDBM50152941 4-[4-(2-trifluorobenzyl)hexahydro-1-pyridinyl]spiro[cyclohexane-1,6''-(6'',8''-dihydro[1,3]dioxolo[5,4-e]isobenzofuran)]-8''-one::CHEMBL362298

SMILES FC(F)(F)c1ccccc1CC1CCN(CC1)[C@H]1CC[C@]2(CC1)OC(=O)c1c3OCOc3ccc21

InChI Key InChIKey=RRFURIBDRXRPMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152941   

TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152941(4-[4-(2-trifluorobenzyl)hexahydro-1-pyridinyl]spir...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed