BDBM50152992 1-[1-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-2-hydroxy-propyl)-3-(4-chloro-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone::CHEMBL180232

SMILES CC(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=JOMUOBXQCQBUHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152992   

TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50152992(1-[1-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazi...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50152992(1-[1-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against human cysteine protease cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed