BDBM50153360 CHEMBL3774784

SMILES CCCCCCNC(=O)Oc1cccc(c1)-c1ccc(cc1F)[C@H](C)C(O)=O

InChI Key InChIKey=USQOVYLRWBOSQC-HNNXBMFYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153360   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50153360(CHEMBL3774784)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human COX2 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic aci...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50153360(CHEMBL3774784)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of ovine COX1 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic acid as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50153360(CHEMBL3774784)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain homogenates preincubated for 10 mins followed by addition of substrate measured after 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed