BDBM50153382 CHEMBL183289::Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-methyl-propoxy)-benzylcarbamoyl]-pyrrolidin-1-yl}-3-oxo-1-pentafluorophenylmethyl-propyl-ammonium;

SMILES CC(C)[C@@H](Oc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)CC([NH3+])Cc2c(F)c(F)c(F)c(F)c2F)cc1)C(O)=O

InChI Key InChIKey=MAKUSAJTXWUWHK-UHFFFAOYSA-O

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50153382   

TargetDipeptidyl peptidase 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153382(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human recombinant Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153382(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of Fibroblast activation protein alpha (seprase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153382(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Potassium channel HERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153382(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase IXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153382(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of prolyl endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153382(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153382(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Quiescent cell prolyl dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153382(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase VIIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed