BDBM50153384 CHEMBL364102::Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-methyl-propoxy)-benzylcarbamoyl]-pyrrolidin-1-yl}-1-(2,5-difluoro-benzyl)-3-oxo-propyl-ammonium;

SMILES CC(C)[C@@H](Oc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)CC([NH3+])Cc2cc(F)ccc2F)cc1)C(O)=O

InChI Key InChIKey=GERHAXJHCLVDBJ-UHFFFAOYSA-O

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50153384   

TargetDipeptidyl peptidase 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153384(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of human recombinant Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153384(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Fibroblast activation protein alpha (seprase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153384(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of prolyl endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153384(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of human Potassium channel HERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153384(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of Dipeptidylpeptidase IXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153384(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Quiescent cell prolyl dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153384(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase VIIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153384(Trifluoro-acetate3-{(S)-2-[4-((R)-1-carboxy-2-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed