BDBM50153386 CHEMBL435882::Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-2-(4-trifluoromethyl-benzylcarbamoyl)-pyrrolidin-1-yl]-propyl-ammonium;

SMILES [NH3+]C(CC(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(F)(F)F)Cc1ccccc1F

InChI Key InChIKey=BCERHNLMUQCEJQ-UHFFFAOYSA-O

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50153386   

TargetDipeptidyl peptidase 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-...)
Affinity DataIC50: 721nMAssay Description:Inhibition of human recombinant Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153386(Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-...)
Affinity DataIC50: 870nMAssay Description:Inhibition of human Potassium channel HERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Dipeptidylpeptidase VIIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of Quiescent cell prolyl dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Fibroblast activation protein alpha (seprase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase IXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed