BDBM50153431 1-Ethyl-3-{3-[2-(4-phenyl-butyl)-benzofuran-4-yl]-propyl}-urea::CHEMBL183962

SMILES CCNC(=O)NCCCc1cccc2oc(CCCCc3ccccc3)cc12

InChI Key InChIKey=JRWLPMZKOAKSJV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153431   

TargetMelatonin receptor type 1A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153431(1-Ethyl-3-{3-[2-(4-phenyl-butyl)-benzofuran-4-yl]-...)
Affinity DataKi:  21nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to membrane preparations of NIH3T3 cells stably expressing human Melatonin receptor type 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153431(1-Ethyl-3-{3-[2-(4-phenyl-butyl)-benzofuran-4-yl]-...)
Affinity DataKi:  52nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to membrane preparations of NIH3T3 cells stably expressing human Melatonin receptor type 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed