BDBM50153448 3-(3-Chloro-phenylamino)-4-[1-(3-dimethylamino-propyl)-1H-indol-3-yl]-pyrrole-2,5-dione::CHEMBL364337

SMILES CN(C)CCCn1cc(C2=C(Nc3cccc(Cl)c3)C(=O)NC2=O)c2ccccc12

InChI Key InChIKey=DPTJTWOSTGZPKA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50153448   

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153448(3-(3-Chloro-phenylamino)-4-[1-(3-dimethylamino-pro...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153448(3-(3-Chloro-phenylamino)-4-[1-(3-dimethylamino-pro...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153448(3-(3-Chloro-phenylamino)-4-[1-(3-dimethylamino-pro...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProtein kinase C alpha type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153448(3-(3-Chloro-phenylamino)-4-[1-(3-dimethylamino-pro...)
Affinity DataIC50: 558nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153448(3-(3-Chloro-phenylamino)-4-[1-(3-dimethylamino-pro...)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed