BDBM50153450 3-(1H-Indol-3-yl)-4-phenylamino-pyrrole-2,5-dione::CHEMBL183310

SMILES O=C1NC(=O)C(=C1Nc1ccccc1)c1c[nH]c2ccccc12

InChI Key InChIKey=WEKZVKNLORTLQV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50153450   

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153450(3-(1H-Indol-3-yl)-4-phenylamino-pyrrole-2,5-dione ...)
Affinity DataIC50: 223nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153450(3-(1H-Indol-3-yl)-4-phenylamino-pyrrole-2,5-dione ...)
Affinity DataIC50: 223nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153450(3-(1H-Indol-3-yl)-4-phenylamino-pyrrole-2,5-dione ...)
Affinity DataIC50: 224nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153450(3-(1H-Indol-3-yl)-4-phenylamino-pyrrole-2,5-dione ...)
Affinity DataIC50: 395nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153450(3-(1H-Indol-3-yl)-4-phenylamino-pyrrole-2,5-dione ...)
Affinity DataIC50: 7.23E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153450(3-(1H-Indol-3-yl)-4-phenylamino-pyrrole-2,5-dione ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed