BDBM50153452 3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-m-tolylamino-pyrrole-2,5-dione::CHEMBL369114

SMILES CN(C)CCCn1cc(C2=C(Nc3cccc(C)c3)C(=O)NC2=O)c2ccccc12

InChI Key InChIKey=FNZFLGLGSOANLF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50153452   

LigandPNGBDBM50153452(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-m-t...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM50153452(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-m-t...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM50153452(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-m-t...)
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153452(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-m-t...)
Affinity DataIC50: 727nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153452(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-m-t...)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed