BDBM50153455 3-Phenylamino-4-[1-(3-piperidin-1-yl-propyl)-1H-indol-3-yl]-pyrrole-2,5-dione::CHEMBL187235

SMILES O=C1NC(=O)C(=C1Nc1ccccc1)c1cn(CCCN2CCCCC2)c2ccccc12

InChI Key InChIKey=JJIVXGZWNOKEDV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50153455   

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153455(3-Phenylamino-4-[1-(3-piperidin-1-yl-propyl)-1H-in...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153455(3-Phenylamino-4-[1-(3-piperidin-1-yl-propyl)-1H-in...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153455(3-Phenylamino-4-[1-(3-piperidin-1-yl-propyl)-1H-in...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProtein kinase C alpha type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153455(3-Phenylamino-4-[1-(3-piperidin-1-yl-propyl)-1H-in...)
Affinity DataIC50: 726nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153455(3-Phenylamino-4-[1-(3-piperidin-1-yl-propyl)-1H-in...)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed