BDBM50153770 1-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-methyl)-4-oxo-1,4-dihydro-pyridine-3-carbonitrile::CHEMBL184488

SMILES Clc1cccc(c1)-n1cc(C#N)c(=O)cc1CNCc1cncn1Cc1ccc(cc1)C#N

InChI Key InChIKey=PRJQZNMTCLOSFT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153770   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50153770(1-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)Copy SMILESCopy InChI

Affinity DataIC50: 7.90nMAssay Description:Inhibition of Bovine farnesyltransferase (FTase)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50153770(1-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Bovine geranylgeranyltransferase (GGT)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL