BDBM50153973 4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl]-benzenesulfonamide::CHEMBL187274

SMILES NS(=O)(=O)c1ccc(CCNc2nc(Cl)nc(Cl)n2)cc1

InChI Key InChIKey=YJRCEYRKXRXPCA-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50153973   

TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50153973(4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl...)
Affinity DataKi:  15.4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50153973(4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl...)
Affinity DataKi:  21nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50153973(4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50153973(4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl...)
Affinity DataKi:  43.8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50153973(4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl...)
Affinity DataKi:  75nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50153973(4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl...)
Affinity DataKi:  75nMAssay Description:Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50153973(4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl...)
Affinity DataKi:  138nMAssay Description:Inhibitory activity against human carbonic anhydrase IX expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50153973(4-[2-(4,6-Dichloro-[1,3,5]triazin-2-ylamino)-ethyl...)
Affinity DataKi:  138nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed