BDBM50153981 4-[2-(4-Ethoxy-phenyl)-6-methylsulfanyl-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide::CHEMBL186709

SMILES CCOc1ccc(cc1)-c1nn2nc(SC)ccc2c1-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=WQGOWYVBXVBECY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153981   

TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153981(4-[2-(4-Ethoxy-phenyl)-6-methylsulfanyl-pyrazolo[1...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153981(4-[2-(4-Ethoxy-phenyl)-6-methylsulfanyl-pyrazolo[1...)
Affinity DataIC50: 8.63E+3nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed