BDBM50153996 6-Ethyl-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine::CHEMBL187468

SMILES CCc1ccc2c(c(nn2n1)-c1ccc(F)cc1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=CKHSBMPDVLORNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153996   

TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153996(6-Ethyl-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153996(6-Ethyl-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed