BDBM50154034 2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-propyl-1H-imidazol-2-yl)-3,4-dihydro-1H-isoquinolin-2-yl]-propan-1-one::CHEMBL440380

SMILES CCCc1nc([nH]c1C)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=SWRXASXLGINNHP-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50154034   

TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataEC50:  85nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataKi: >100nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataKi: >100nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed