BDBM50154040 2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-2-yl]-3-(4-hydroxy-phenyl)-propan-1-one::CHEMBL362514

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1c1nc2ccccc2[nH]1

InChI Key InChIKey=UUNVLVIBWMJAMY-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50154040   

TargetDelta-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataKi:  15.1nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataKi:  15.1nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataEC50:  37nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed