BDBM50154564 CHEMBL3774835::US10688093, Compound DT2012-0375412::US11701353, Compound DT2012-0375412

SMILES COc1cccc(c1)-n1c(N)c(C(N)=O)c2nc3ccccc3nc12

InChI Key InChIKey=CHHKMVNVTYIPGZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154564   

TargetEphrin type-B receptor 4(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50154564(CHEMBL3774835 | US10688093, Compound DT2012-037541...)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal GST-fused His6-tagged human recombinant EphB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50154564(CHEMBL3774835 | US10688093, Compound DT2012-037541...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human EPHB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50154564(CHEMBL3774835 | US10688093, Compound DT2012-037541...)
Affinity DataIC50: 1.19E+3nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent