BDBM50154975 2-[2-(3-Phenoxy-phenyl)-2H-tetrazol-5-yl]-pyridine::CHEMBL186521

SMILES O(c1ccccc1)c1cccc(c1)-n1nnc(n1)-c1ccccn1

InChI Key InChIKey=XIULEDQKPVUSNS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154975   

TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50154975(2-[2-(3-Phenoxy-phenyl)-2H-tetrazol-5-yl]-pyridine...)
Affinity DataKi:  617nMAssay Description:Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortical...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50154975(2-[2-(3-Phenoxy-phenyl)-2H-tetrazol-5-yl]-pyridine...)
Affinity DataIC50: 1.46E+3nMAssay Description:Antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assay using glutamate (10 uM) as agonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed