BDBM50155235 CHEMBL186470::N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-methyl-benzothiazol-6-yl)-acetamide

SMILES Cc1nc2ccc(CC(=O)Nc3ncc(s3)C3CCC3)cc2s1

InChI Key InChIKey=YZXFATFOBBTPIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155235   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155235(CHEMBL186470 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-...)
Affinity DataIC50:  16nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155235(CHEMBL186470 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-...)
Affinity DataIC50:  12nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed