BDBM50155318 CHEMBL3781063

SMILES CSc1ccc(cc1)C(=O)\C=C\c1cccc2OCOc12

InChI Key InChIKey=GKDHWOUMCGRQHR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155318   

TargetAmine oxidase [flavin-containing] B(Human)
Qatar University

Curated by ChEMBL
LigandPNGBDBM50155318(CHEMBL3781063)
Affinity DataKi:  550nMAssay Description:Competitive inhibition of human MAOB overexpressed in Pichia pastoris using MMTP as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Qatar University

Curated by ChEMBL
LigandPNGBDBM50155318(CHEMBL3781063)
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrate incubated for 15 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Qatar University

Curated by ChEMBL
LigandPNGBDBM50155318(CHEMBL3781063)
Affinity DataIC50: 950nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected BTI insect cell microsomes using MMTP as substrate preincubated for 5 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed